Essential Roles of BCCIP in Mouse Embryonic Development and Structural Stability of Chromosomes

BCCIP is a BRCA2- and CDKN1A(p21)-interacting protein that has been implicated in the maintenance of genomic integrity. To understand the in vivo functions of BCCIP, we generated a conditional BCCIP knockdown transgenic mouse model using Cre-LoxP mediated RNA interference. The BCCIP knockdown embryo...

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Detalles Bibliográficos
Autores principales: Lu, Huimei, Huang, Yi-Yuan, Mehrotra, Sonam, Droz-Rosario, Roberto, Liu, Jingmei, Bhaumik, Mantu, White, Eileen, Shen, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178617/
https://www.ncbi.nlm.nih.gov/pubmed/21966279
http://dx.doi.org/10.1371/journal.pgen.1002291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178617/
https://www.ncbi.nlm.nih.gov/pubmed/21966279
http://dx.doi.org/10.1371/journal.pgen.1002291

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