The opposing roles of E2A and Id3 that orchestrate and enforce the naïve T cell fate

It is established that E2A and its antagonist, Id3, modulate developmental progression at the pre-TCR receptor (pre-TCR) and TCR checkpoints. Here we demonstrate that Id3 expression is elevated beyond the pre-TCR checkpoint, remains high in naive T cells and shows a bimodal pattern in the effector/m...

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Detalles Bibliográficos
Autores principales: Miyazaki, Masaki, Rivera, Richard R, Miyazaki, Kazuko, Lin, Yin C, Agata, Yasutoshi, Murre, Cornelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178719/
https://www.ncbi.nlm.nih.gov/pubmed/21857655
http://dx.doi.org/10.1038/ni.2086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178719/
https://www.ncbi.nlm.nih.gov/pubmed/21857655
http://dx.doi.org/10.1038/ni.2086

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