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Identification of QTL genes for BMD variation using both linkage and gene-based association approaches

Low bone mineral density (BMD) is a risk factor for osteoporotic fracture with a high heritability. Previous large scale linkage study in Northern Chinese has identified four significant quantitative trait loci (QTL) for BMD variation on chromosome 2q24, 5q21, 7p21 and 13q21. We performed a replicat...

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Detalles Bibliográficos
Autores principales: Li, Gloria Hoi-Yee, Cheung, Ching-Lung, Xiao, Su-Mei, Lau, Kam-Shing, Gao, Yi, Bow, Cora H., Huang, Qing-Yang, Sham, Pak-Chung, Kung, Annie Wai-Chee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178777/
https://www.ncbi.nlm.nih.gov/pubmed/21424381
http://dx.doi.org/10.1007/s00439-011-0972-2