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JNK Isoforms Differentially Regulate Neurite Growth and Regeneration in Dopaminergic Neurons In Vitro

Parkinson’s disease is characterized by selective and progressive loss of midbrain DAergic neurons (MDN) in the substantia nigra and degeneration of its nigrostriatal projections. Whereas the cellular pathophysiology has been closely linked to an activation of c-Jun N-terminal kinases (JNKs) and c-J...

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Detalles Bibliográficos
Autores principales: Tönges, Lars, Planchamp, Veronique, Koch, Jan-Christoph, Herdegen, Thomas, Bähr, Mathias, Lingor, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Humana Press Inc 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178779/
https://www.ncbi.nlm.nih.gov/pubmed/21468718
http://dx.doi.org/10.1007/s12031-011-9519-1