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The effect of ageing on phenotype and function of monocyte-derived Langerhans cells

BACKGROUND: With increasing age the immune system shows functional decline. In the skin this is associated with an increased incidence of epidermal malignancies and infections. Epidermal Langerhans cells (LCs) act as sentinels of the immune system, recognizing, processing and presenting antigen and...

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Detalles Bibliográficos
Autores principales: Ogden, S, Dearman, RJ, Kimber, I, Griffiths, CEM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178785/
https://www.ncbi.nlm.nih.gov/pubmed/21410677
http://dx.doi.org/10.1111/j.1365-2133.2011.10313.x