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A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-κB for degradation

Many bacterial pathogens utilize a type III secretion system (T3SS) to inject virulence effector proteins into host cells during infection. Previously, we found that enteropathogenic Escherichia coli (EPEC) uses the type III effector, NleE, to block the inflammatory response by inhibiting IκB degrad...

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Detalles Bibliográficos
Autores principales: Pearson, Jaclyn S, Riedmaier, Patrice, Marchès, Olivier, Frankel, Gad, Hartland, Elizabeth L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178796/
https://www.ncbi.nlm.nih.gov/pubmed/21306441
http://dx.doi.org/10.1111/j.1365-2958.2011.07568.x