Structural Chemistry of Human SET Domain Protein Methyltransferases

There are about fifty SET domain protein methyltransferases (PMTs) in the human genome, that transfer a methyl group from S-adenosyl-L-methionine (SAM) to substrate lysines on histone tails or other peptides. A number of structures in complex with cofactor, substrate, or inhibitors revealed the mech...

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Detalles Bibliográficos
Autor principal: Schapira, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178901/
https://www.ncbi.nlm.nih.gov/pubmed/21966348
http://dx.doi.org/10.2174/1875397301005010085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178901/
https://www.ncbi.nlm.nih.gov/pubmed/21966348
http://dx.doi.org/10.2174/1875397301005010085

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