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Structural Chemistry of Human SET Domain Protein Methyltransferases

There are about fifty SET domain protein methyltransferases (PMTs) in the human genome, that transfer a methyl group from S-adenosyl-L-methionine (SAM) to substrate lysines on histone tails or other peptides. A number of structures in complex with cofactor, substrate, or inhibitors revealed the mech...

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Detalles Bibliográficos
Autor principal:	Schapira, Matthieu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178901/ https://www.ncbi.nlm.nih.gov/pubmed/21966348 http://dx.doi.org/10.2174/1875397301005010085

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