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Synthesis and Biological Evaluation of Ezetimibe Analogs as Possible Cholesterol Absorption Inhibitors

In order to investigate the SAR of Ezetimibe analogs for cholesterol absorption inhibitions, amide group and electron-deficient pyridine ring were introduced to the C-(3) carbon chain of Ezetimibe. Eight new derivatives of the 2-azetidinone cholesterol absorption inhibitors have been synthesized, an...

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Detalles Bibliográficos
Autores principales:	Wang, Yubin, Haiqian, Huang, Wenlong, Zhang, Huibin, Zhou, Jinpei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers Ltd 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179128/ https://www.ncbi.nlm.nih.gov/pubmed/21966284 http://dx.doi.org/10.2174/157018011795906776

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