Combined 3D-QSAR and Docking Modelling Study on Indolocarbazole Series Compounds as Tie-2 Inhibitors

Tie-2, a kind of endothelial cell tyrosine kinase receptor, is required for embryonic blood vessel development and tumor angiogenesis. Several compounds that showed potent activity toward this attractive anticancer drug target in the assay have been reported. In order to investigate the structure-ac...

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Detalles Bibliográficos
Autores principales: Tian, Yuanxin, Xu, Jian, Li, Zhonghuang, Zhu, Zhengguang, Zhang, Jiajie, Wu, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179154/
https://www.ncbi.nlm.nih.gov/pubmed/21954347
http://dx.doi.org/10.3390/ijms12085080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179154/
https://www.ncbi.nlm.nih.gov/pubmed/21954347
http://dx.doi.org/10.3390/ijms12085080

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