Continuous Elevation of PTH Increases the Number of Osteoblasts via Both Osteoclast-Dependent and -Independent Mechanisms

Sustained parathyroid hormone (PTH) elevation stimulates bone remodeling (ie, both resorption and formation). The former results from increased RANKL synthesis, but the cause of the latter has not been established. Current hypotheses include release of osteoblastogenic factors from osteoclasts or fr...

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Detalles Bibliográficos
Autores principales: Jilka, Robert L, O'Brien, Charles A, Bartell, Shoshana M, Weinstein, Robert S, Manolagas, Stavros C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179285/
https://www.ncbi.nlm.nih.gov/pubmed/20533302
http://dx.doi.org/10.1002/jbmr.145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179285/
https://www.ncbi.nlm.nih.gov/pubmed/20533302
http://dx.doi.org/10.1002/jbmr.145

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