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Skeletal Recovery After Weaning Does Not Require PTHrP

Mice lose 20% to 25% of trabecular bone mineral content (BMC) during lactation and restore it after weaning through unknown mechanisms. We found that tibial Pthrp mRNA expression was upregulated fivefold by 7 days after weaning versus end of lactation in wild-type (WT) mice. To determine whether par...

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Detalles Bibliográficos
Autores principales: Kirby, Beth J, Ardeshirpour, Laleh, Woodrow, Janine P, Wysolmerski, John J, Sims, Natalie A, Karaplis, Andrew C, Kovacs, Christopher S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179289/
https://www.ncbi.nlm.nih.gov/pubmed/21308774
http://dx.doi.org/10.1002/jbmr.339