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Impact of Maturational Status on the Ability of Osteoblasts to Enhance the Hematopoietic Function of Stem and Progenitor Cells

Osteoblasts (OBs) exert a prominent regulatory effect on hematopoietic stem cells (HSCs). We evaluated the difference in hematopoietic expansion and function in response to co-culture with OBs at various stages of development. Murine calvarial OBs were seeded directly (fresh) or cultured for 1, 2, o...

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Detalles Bibliográficos
Autores principales: Cheng, Ying-Hua, Chitteti, Brahmananda R, Streicher, Drew A, Morgan, Joseph A, Rodriguez-Rodriguez, Sonia, Carlesso, Nadia, Srour, Edward F, Kacena, Melissa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179304/
https://www.ncbi.nlm.nih.gov/pubmed/21542011
http://dx.doi.org/10.1002/jbmr.302