Astacin Proteases Cleave Dentin Sialophosphoprotein (Dspp) to Generate Dentin Phosphoprotein (Dpp)

Dentin sialophosphoprotein (Dspp) is critical for proper dentin biomineralization because genetic defects in DSPP cause dentin dysplasia type II and dentinogenesis imperfecta types II and III. Dspp is processed by proteases into smaller subunits; the initial cleavage releases dentin phosphoprotein (...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Shuhei, Simmer, James P, Hu, Jan C-C, Richardson, Amelia S, Yamakoshi, Fumiko, Yamakoshi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179315/
https://www.ncbi.nlm.nih.gov/pubmed/20687161
http://dx.doi.org/10.1002/jbmr.202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179315/
https://www.ncbi.nlm.nih.gov/pubmed/20687161
http://dx.doi.org/10.1002/jbmr.202

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