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Polymorphisms in Predicted miRNA Binding Sites and Osteoporosis

MicroRNAs (miRNAs) regulate posttranscriptional gene expression usually by binding to 3'-untranslated regions (3'-UTRs) of target message RNAs (mRNAs). Hence genetic polymorphisms on 3'-UTRs of mRNAs may alter binding affinity between miRNAs target 3'-UTRs, thereby altering trans...

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Detalles Bibliográficos
Autores principales: Lei, Shu-Feng, Papasian, Christopher J, Deng, Hong-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179316/
https://www.ncbi.nlm.nih.gov/pubmed/20641033
http://dx.doi.org/10.1002/jbmr.186