Identification of the Homeobox Protein Prx1 (MHox, Prrx-1) as a Regulator of Osterix Expression and Mediator of Tumor Necrosis Factor α Action in Osteoblast Differentiation

Tumor necrosis factor α (TNF-α) promotes bone loss and inhibits bone formation. Osterix (Osx, SP7) is a transcription factor required for osteoblast (OB) differentiation because deletion results in a cartilaginous skeleton. We previously described a TNF suppressor element in the Osx promoter that wa...

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Detalles Bibliográficos
Autores principales: Lu, Xianghuai, Beck, George R, Gilbert, Linda C, Camalier, Corinne E, Bateman, Nicholas W, Hood, Brian L, Conrads, Thomas P, Kern, Michael J, You, Shaojin, Chen, Hong, Nanes, Mark S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179318/
https://www.ncbi.nlm.nih.gov/pubmed/20683885
http://dx.doi.org/10.1002/jbmr.203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179318/
https://www.ncbi.nlm.nih.gov/pubmed/20683885
http://dx.doi.org/10.1002/jbmr.203

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