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The Biological Function of DMP-1 in Osteocyte Maturation Is Mediated by Its 57-kDa C-terminal Fragment

Dentin matrix protein 1 (DMP-1) is a key molecule in controlling osteocyte formation and phosphate homeostasis. Based on observations that full-length DMP-1 is not found in bone, but only cleaved fragments of 37 and 57 kDa are present, and in view of the finding that mutations in the 57-kDa fragment...

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Detalles Bibliográficos
Autores principales: Lu, Yongbo, Yuan, Baozhi, Qin, Chunlin, Cao, Zhengguo, Xie, Yixia, Dallas, Sarah L, McKee, Marc D, Drezner, Marc K, Bonewald, Lynda F, Feng, Jian Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179348/
https://www.ncbi.nlm.nih.gov/pubmed/20734454
http://dx.doi.org/10.1002/jbmr.226