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Decline of influenza-specific CD8(+ )T cell repertoire in healthy geriatric donors

BACKGROUND: While influenza vaccination results in protective antibodies against primary infections, clearance of infection is primarily mediated through CD8(+ )T cells. Studying the CD8(+ )T cell response to influenza epitopes is crucial in understanding the disease associated morbidity and mortali...

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Detalles Bibliográficos
Autores principales: Lee, Jessica B, Oelke, Mathias, Ramachandra, Lakshmi, Canaday, David H, Schneck, Jonathan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179433/
https://www.ncbi.nlm.nih.gov/pubmed/21846352
http://dx.doi.org/10.1186/1742-4933-8-6