Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251

Glioblastoma multiforme (GBM) carries a dismal prognosis primarily due to its aggressive proliferation in the brain regulated by complex molecular mechanisms. One promising molecular target in GBM is over-expressed basic fibroblast growth factor (bFGF), which has been correlated with growth, progres...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Xu, Xinnv, Feng, Xuequan, Zhang, Biao, Wang, Jinhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179445/
https://www.ncbi.nlm.nih.gov/pubmed/21906308
http://dx.doi.org/10.1186/1756-9966-30-80

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179445/
https://www.ncbi.nlm.nih.gov/pubmed/21906308
http://dx.doi.org/10.1186/1756-9966-30-80

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