Tumor cell-selective apoptosis induction through targeting of K(V)10.1 via bifunctional TRAIL antibody

BACKGROUND: The search for strategies to target ion channels for therapeutic applications has become of increasing interest. Especially, the potassium channel K(V)10.1 (Ether-á-go-go) is attractive as target since this surface protein is virtually not detected in normal tissue outside the central ne...

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Detalles Bibliográficos
Autores principales: Hartung, Franziska, Stühmer, Walter, Pardo, Luis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179451/
https://www.ncbi.nlm.nih.gov/pubmed/21899742
http://dx.doi.org/10.1186/1476-4598-10-109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179451/
https://www.ncbi.nlm.nih.gov/pubmed/21899742
http://dx.doi.org/10.1186/1476-4598-10-109

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