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Tumor cell-selective apoptosis induction through targeting of K(V)10.1 via bifunctional TRAIL antibody
BACKGROUND: The search for strategies to target ion channels for therapeutic applications has become of increasing interest. Especially, the potassium channel K(V)10.1 (Ether-á-go-go) is attractive as target since this surface protein is virtually not detected in normal tissue outside the central ne...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179451/ https://www.ncbi.nlm.nih.gov/pubmed/21899742 http://dx.doi.org/10.1186/1476-4598-10-109 |