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No Effect of Folic Acid Supplementation on Global DNA Methylation in Men and Women with Moderately Elevated Homocysteine

A global loss of cytosine methylation in DNA has been implicated in a wide range of diseases. There is growing evidence that modifications in DNA methylation can be brought about by altering the intake of methyl donors such as folate. We examined whether long-term daily supplementation with 0.8 mg o...

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Detalles Bibliográficos
Autores principales: Jung, Audrey Y., Smulders, Yvo, Verhoef, Petra, Kok, Frans J., Blom, Henk, Kok, Robert M., Kampman, Ellen, Durga, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179474/
https://www.ncbi.nlm.nih.gov/pubmed/21966393
http://dx.doi.org/10.1371/journal.pone.0024976