The Molecular Assembly of Amyloid Aβ Controls Its Neurotoxicity and Binding to Cellular Proteins

Accumulation of β-sheet-rich peptide (Aβ) is strongly associated with Alzheimer's disease, characterized by reduction in synapse density, structural alterations of dendritic spines, modification of synaptic protein expression, loss of long-term potentiation and neuronal cell death. Aβ species a...

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Detalles Bibliográficos
Autores principales: Manzoni, Claudia, Colombo, Laura, Bigini, Paolo, Diana, Valentina, Cagnotto, Alfredo, Messa, Massimo, Lupi, Monica, Bonetto, Valentina, Pignataro, Mauro, Airoldi, Cristina, Sironi, Erika, Williams, Alun, Salmona, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179491/
https://www.ncbi.nlm.nih.gov/pubmed/21966382
http://dx.doi.org/10.1371/journal.pone.0024909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179491/
https://www.ncbi.nlm.nih.gov/pubmed/21966382
http://dx.doi.org/10.1371/journal.pone.0024909

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