Cargando…
Tumor Suppressor p53 Functions as a Negative Regulator in IgE-Mediated Mast Cell Activation
Mast cells are known to play a pivotal role in allergic diseases such as allergic rhinitis, asthma, and atopic dermatitis by releasing granules containing histamine, LTC4, and other preformed chemical mediators. Previous reports have demonstrated that IKK2 (also called IKKβ), a central intracellular...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179515/ https://www.ncbi.nlm.nih.gov/pubmed/21966524 http://dx.doi.org/10.1371/journal.pone.0025412 |