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Tumor Suppressor p53 Functions as a Negative Regulator in IgE-Mediated Mast Cell Activation

Mast cells are known to play a pivotal role in allergic diseases such as allergic rhinitis, asthma, and atopic dermatitis by releasing granules containing histamine, LTC4, and other preformed chemical mediators. Previous reports have demonstrated that IKK2 (also called IKKβ), a central intracellular...

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Detalles Bibliográficos
Autores principales: Suzuki, Kotaro, Murphy, Samantha H., Xia, Yifeng, Yokota, Masaya, Nakagomi, Daiki, Liu, Fei, Verma, Inder M., Nakajima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179515/
https://www.ncbi.nlm.nih.gov/pubmed/21966524
http://dx.doi.org/10.1371/journal.pone.0025412