The De-Ubiquitinylating Enzyme, USP2, Is Associated with the Circadian Clockwork and Regulates Its Sensitivity to Light

We have identified a novel component of the circadian clock that regulates its sensitivity to light at the evening light to dark transition. USP2 (Ubiquitin Specific Protease 2), which de-ubiquitinylates and stabilizes target proteins, is rhythmically expressed in multiple tissues including the SCN....

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Detalles Bibliográficos
Autores principales: Scoma, Heather Dehlin, Humby, Monica, Yadav, Geetha, Zhang, Qingjiong, Fogerty, Joseph, Besharse, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179520/
https://www.ncbi.nlm.nih.gov/pubmed/21966515
http://dx.doi.org/10.1371/journal.pone.0025382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179520/
https://www.ncbi.nlm.nih.gov/pubmed/21966515
http://dx.doi.org/10.1371/journal.pone.0025382

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