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MU2 and HP1a Regulate the Recognition of Double Strand Breaks in Drosophila melanogaster

Chromatin structure regulates the dynamics of the recognition and repair of DNA double strand breaks; open chromatin enhances the recruitment of DNA damage response factors, while compact chromatin is refractory to the assembly of radiation-induced repair foci. MU2, an orthologue of human MDC1, a sc...

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Detalles Bibliográficos
Autores principales: Dronamraju, Raghuvar, Mason, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179522/
https://www.ncbi.nlm.nih.gov/pubmed/21966530
http://dx.doi.org/10.1371/journal.pone.0025439