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MU2 and HP1a Regulate the Recognition of Double Strand Breaks in Drosophila melanogaster
Chromatin structure regulates the dynamics of the recognition and repair of DNA double strand breaks; open chromatin enhances the recruitment of DNA damage response factors, while compact chromatin is refractory to the assembly of radiation-induced repair foci. MU2, an orthologue of human MDC1, a sc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179522/ https://www.ncbi.nlm.nih.gov/pubmed/21966530 http://dx.doi.org/10.1371/journal.pone.0025439 |