Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models

Recent technological advances have opened the door for the fast and cost-effective generation of genetically engineered mouse models (GEMMs) to study cancer. We describe here a conceptually novel approach for the generation of chimeric GEMMs based on the controlled introduction of various genetic el...

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Detalles Bibliográficos
Autores principales: Huijbers, Ivo J, Krimpenfort, Paul, Berns, Anton, Jonkers, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Prospects & Overviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179600/
https://www.ncbi.nlm.nih.gov/pubmed/21735458
http://dx.doi.org/10.1002/bies.201100018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179600/
https://www.ncbi.nlm.nih.gov/pubmed/21735458
http://dx.doi.org/10.1002/bies.201100018

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