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Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models

Recent technological advances have opened the door for the fast and cost-effective generation of genetically engineered mouse models (GEMMs) to study cancer. We describe here a conceptually novel approach for the generation of chimeric GEMMs based on the controlled introduction of various genetic el...

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Detalles Bibliográficos
Autores principales:	Huijbers, Ivo J, Krimpenfort, Paul, Berns, Anton, Jonkers, Jos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2011
Materias:	Prospects & Overviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179600/ https://www.ncbi.nlm.nih.gov/pubmed/21735458 http://dx.doi.org/10.1002/bies.201100018

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