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Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway

BACKGROUND: Rab GTPases function as modulators in intracellular transport. Rab5a, a member of the Rab subfamily of small GTPases, is an important regulator of vesicle traffic from the plasma membrane to early endosomes. Recent findings have reported that Rab5a gene was involved in the progression of...

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Detalles Bibliográficos
Autores principales: Liu, Shan-shan, Chen, Xiang-mei, Zheng, Hong-xia, Shi, Shu-liang, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179705/
https://www.ncbi.nlm.nih.gov/pubmed/21849022
http://dx.doi.org/10.1186/1423-0127-18-58