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Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets
BACKGROUND: Blood platelets undergo a carefully regulated change in shape to serve as the primary mediators of hemostasis and thrombosis. These processes manifest through platelet spreading and aggregation and are dependent on platelet actin cytoskeletal changes orchestrated by the Rho GTPase family...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179747/ https://www.ncbi.nlm.nih.gov/pubmed/21884615 http://dx.doi.org/10.1186/1750-2187-6-11 |