Cargando…

Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

BACKGROUND: Blood platelets undergo a carefully regulated change in shape to serve as the primary mediators of hemostasis and thrombosis. These processes manifest through platelet spreading and aggregation and are dependent on platelet actin cytoskeletal changes orchestrated by the Rho GTPase family...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aslan, Joseph E, Spencer, Alex M, Loren, Cassandra P, Pang, Jiaqing, Welch, Heidi C, Greenberg, Daniel L, McCarty, Owen JT
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179747/ https://www.ncbi.nlm.nih.gov/pubmed/21884615 http://dx.doi.org/10.1186/1750-2187-6-11

Ejemplares similares

Small-molecule inhibitors of P-Rex guanine-nucleotide exchange factors
por: Lawson, CD, et al.
Publicado: (2022)

Regulation of the mTOR-Rac1 axis in platelet function
por: Aslan, Joseph E., et al.
Publicado: (2012)

Control of Cerebellar Long-Term Potentiation by P-Rex-Family Guanine-Nucleotide Exchange Factors and Phosphoinositide 3-Kinase
por: Jackson, Claire, et al.
Publicado: (2010)

P-Rex2, a Rac-guanine nucleotide exchange factor, is expressed selectively in ribbon synaptic terminals of the mouse retina
por: Sherry, David M, et al.
Publicado: (2013)

Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1
por: Pan, Dingxin, et al.
Publicado: (2016)

Regulation and function of P-Rex family Rac-GEFs
por: Welch, Heidi CE
Publicado: (2015)

Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors
por: Marei, Hadir, et al.
Publicado: (2016)

Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors
por: Arthur, William T., et al.
Publicado: (2004)

Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma
por: Lavictoire, Sylvie J., et al.
Publicado: (2021)

A Rac1-Independent Role for P-Rex1 in Melanoblasts
por: Lindsay, Colin R, et al.
Publicado: (2015)

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration
por: Marei, Hadir, et al.
Publicado: (2016)

Data detailing the platelet acetyl-lysine proteome
por: Aslan, Joseph E., et al.
Publicado: (2015)

The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho
por: van Leeuwen, Frank N., et al.
Publicado: (1997)

Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation
por: Murray, D W, et al.
Publicado: (2014)

Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation
por: Kang, In Soon, et al.
Publicado: (2020)

The many faces of the guanine-nucleotide exchange factor trio
por: van Rijssel, Jos, et al.
Publicado: (2012)

Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype
por: Charron, Yves, et al.
Publicado: (2019)

Trapp Stimulates Guanine Nucleotide Exchange on Ypt1p
por: Wang, Wei, et al.
Publicado: (2000)

Scambio, a novel guanine nucleotide exchange factor for Rho
por: Curtis, Christina, et al.
Publicado: (2004)

The Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor Intersectin
por: Ahmad, K. Farid, et al.
Publicado: (2010)

Quantitative Analysis of Guanine Nucleotide Exchange Factors (GEFs) as Enzymes
por: Randazzo, Paul A, et al.
Publicado: (2014)

Structural biology of DOCK‐family guanine nucleotide exchange factors
por: Boland, Andreas, et al.
Publicado: (2022)

The Guanine-Nucleotide Exchange Factor SGEF Plays a Crucial Role in the Formation of Atherosclerosis
por: Samson, Thomas, et al.
Publicado: (2013)

The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1α and Glut-1 Expression and Glucose Uptake in the Brain
por: Hong, Jaewoo, et al.
Publicado: (2020)

Guanine Nucleotide Exchange Factor 7B (RopGEF7B) is involved in floral organ development in Oryza sativa
por: Huang, Jiaqing, et al.
Publicado: (2018)

Chlamydial Entry Involves TARP Binding of Guanine Nucleotide Exchange Factors
por: Lane, B. Josh, et al.
Publicado: (2008)

Zizimin and Dock guanine nucleotide exchange factors in cell function and disease
por: Pakes, Nicholl K., et al.
Publicado: (2013)

Insights into the biological functions of Dock family guanine nucleotide exchange factors
por: Laurin, Mélanie, et al.
Publicado: (2014)

Rac1 Activation Caused by Membrane Translocation of a Guanine Nucleotide Exchange Factor in Akt2-Mediated Insulin Signaling in Mouse Skeletal Muscle
por: Takenaka, Nobuyuki, et al.
Publicado: (2016)

Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells
por: Rosenberg, Brian J., et al.
Publicado: (2017)

Protocol for fluorescence-activated cell sorting of human EpCAM(+) lung cancer cells for gene expression analysis of Rac guanine-nucleotide exchange factors
por: Sullivan, Neil T., et al.
Publicado: (2022)

Upregulation of PIP3-Dependent Rac Exchanger 1 (P-Rex1) Promotes Prostate Cancer Metastasis
por: Qin, Jianbing, et al.
Publicado: (2009)

The Sec7 Guanine Nucleotide Exchange Factor GBF1 Regulates Membrane Recruitment of BIG1 and BIG2 Guanine Nucleotide Exchange Factors to the Trans-Golgi Network (TGN)
por: Lowery, Jason, et al.
Publicado: (2013)

EspM2 is a RhoA guanine nucleotide exchange factor
por: Arbeloa, Ana, et al.
Publicado: (2010)

The emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases
por: Droppelmann, Cristian A., et al.
Publicado: (2014)

Activation of G Proteins by Guanine Nucleotide Exchange Factors Relies on GTPase Activity
por: Stanley, Rob J., et al.
Publicado: (2016)

The Role of Trio, a Rho Guanine Nucleotide Exchange Factor, in Glomerular Podocytes
por: Maier, Mirela, et al.
Publicado: (2018)

Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration
por: Zaritsky, Assaf, et al.
Publicado: (2017)

Role of the Guanine Nucleotide Exchange Factor GBF1 in the Replication of RNA Viruses
por: Martínez, José L., et al.
Publicado: (2020)

BuGZ exhibits guanine nucleotide exchange factor activity toward tubulin
por: Yon, Wesley J., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_febjn191m2n4hk9mdtooli4n34