A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53

Human tumors are heterogeneous and evolve through a dynamic process of genetic mutation and selection. During this process, the effects of a specific mutation on the incipient cancer cell may dictate the nature of subsequent mutations that can be tolerated or selected for, affecting the rate at whic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jongchan, Roh, Meejeon, Doubinskaia, Irina, Algarroba, Gabriela N., Eltoum, Isam-Eldin A., Abdulkadir, Sarki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179816/
https://www.ncbi.nlm.nih.gov/pubmed/21685943
http://dx.doi.org/10.1038/onc.2011.236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179816/
https://www.ncbi.nlm.nih.gov/pubmed/21685943
http://dx.doi.org/10.1038/onc.2011.236

Ejemplares similares