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β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression

β-arrestins 1 and 2 are multifunctional adaptor proteins originally discovered for their role in desensitizing seven-transmembrane receptor signaling via the heterotrimeric guanine nucleotide binding proteins. Recently identified roles of β-arrestins include regulation of cancer cell chemotaxis and...

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Detalles Bibliográficos
Autores principales: Shenoy, Sudha K., Han, Sang-oh, Zhao, Yu Lin, Hara, Makoto R., Oliver, Timothy, Cao, Yiting, Dewhirst, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179824/
https://www.ncbi.nlm.nih.gov/pubmed/21685944
http://dx.doi.org/10.1038/onc.2011.238