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β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression
β-arrestins 1 and 2 are multifunctional adaptor proteins originally discovered for their role in desensitizing seven-transmembrane receptor signaling via the heterotrimeric guanine nucleotide binding proteins. Recently identified roles of β-arrestins include regulation of cancer cell chemotaxis and...
Autores principales: | Shenoy, Sudha K., Han, Sang-oh, Zhao, Yu Lin, Hara, Makoto R., Oliver, Timothy, Cao, Yiting, Dewhirst, Mark W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179824/ https://www.ncbi.nlm.nih.gov/pubmed/21685944 http://dx.doi.org/10.1038/onc.2011.238 |
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