Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

Macrophages and dendritic cells play key roles in viral infections, providing virus reservoirs that frequently resist anti-viral therapies and linking innate virus detection to anti-viral adaptive immune responses(1,2). HIV-1 fails to transduce dendritic cells and has a reduced ability to transduce...

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Detalles Bibliográficos
Autores principales: Hrecka, Kasia, Hao, Caili, Gierszewska, Magda, Swanson, Selene K., Kesik-Brodacka, Malgorzata, Srivastava, Smita, Florens, Laurence, Washburn, Michael P., Skowronski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179858/
https://www.ncbi.nlm.nih.gov/pubmed/21720370
http://dx.doi.org/10.1038/nature10195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179858/
https://www.ncbi.nlm.nih.gov/pubmed/21720370
http://dx.doi.org/10.1038/nature10195

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