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Involvement of Prohibitin Upregulation in Abrin-Triggered Apoptosis

Abrin (ABR), a protein purified from the seeds of Abrus precatorius, induces apoptosis in various types of cancer cells. However, the detailed mechanism remains largely uncharacterized. By using a cDNA microarray platform, we determined that prohibitin (PHB), a tumor suppressor protein, is significa...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Huei, Peck, Konan, Lin, Jung-Yaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179879/
https://www.ncbi.nlm.nih.gov/pubmed/21961024
http://dx.doi.org/10.1155/2012/605154