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Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops

BACKGROUND: Large surface loops contained within compact protein structures and not involved in catalytic process have been proposed as preferred regions for protein family evolution. These loops are subjected to lower sequence constraints and can evolve rapidly in novel structural variants. A good...

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Detalles Bibliográficos
Autores principales: Giacopuzzi, Edoardo, Barlati, Sergio, Preti, Augusto, Venerando, Bruno, Monti, Eugenio, Borsani, Giuseppe, Bresciani, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179935/
https://www.ncbi.nlm.nih.gov/pubmed/21861893
http://dx.doi.org/10.1186/1471-2091-12-45