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Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops
BACKGROUND: Large surface loops contained within compact protein structures and not involved in catalytic process have been proposed as preferred regions for protein family evolution. These loops are subjected to lower sequence constraints and can evolve rapidly in novel structural variants. A good...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179935/ https://www.ncbi.nlm.nih.gov/pubmed/21861893 http://dx.doi.org/10.1186/1471-2091-12-45 |