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The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases

BACKGROUND: Pathogens depend on peptidase activities to accomplish many physiological processes, including interaction with their hosts, highlighting parasitic peptidases as potential drug targets. In this study, a major leucyl aminopeptidolytic activity was identified in Trypanosoma cruzi, the aeti...

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Detalles Bibliográficos
Autores principales: Cadavid-Restrepo, Gloria, Gastardelo, Thiago S, Faudry, Eric, de Almeida, Hugo, Bastos, Izabela MD, Negreiros, Raquel S, Lima, Meire M, Assumpção, Teresa C, Almeida, Keyla C, Ragno, Michel, Ebel, Christine, Ribeiro, Bergmann M, Felix, Carlos R, Santana, Jaime M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179936/
https://www.ncbi.nlm.nih.gov/pubmed/21861921
http://dx.doi.org/10.1186/1471-2091-12-46