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DNA double-strand break induction in Ku80-deficient CHO cells following Boron Neutron Capture Reaction

BACKGROUND: Boron neutron capture reaction (BNCR) is based on irradiation of tumors after accumulation of boron compound. (10)B captures neutrons and produces an alpha ((4)He) particle and a recoiled lithium nucleus ((7)Li). These particles have the characteristics of high linear energy transfer (LE...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Kinashi, Yuko, Takahashi, Sentaro, Kashino, Genro, Okayasu, Ryuichi, Masunaga, Shinichiro, Suzuki, Minoru, Ono, Koji
Format: Online Artikel Text
Sprache:English
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179943/
https://www.ncbi.nlm.nih.gov/pubmed/21888676
http://dx.doi.org/10.1186/1748-717X-6-106