Scaffold Diversity of Exemplified Medicinal Chemistry Space

[Image: see text] The scaffold diversity of 7 representative commercial and proprietary compound libraries is explored for the first time using both Murcko frameworks and Scaffold Trees. We show that Level 1 of the Scaffold Tree is useful for the characterization of scaffold diversity in compound li...

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Detalles Bibliográficos
Autores principales: Langdon, Sarah R., Brown, Nathan, Blagg, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180201/
https://www.ncbi.nlm.nih.gov/pubmed/21877753
http://dx.doi.org/10.1021/ci2001428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180201/
https://www.ncbi.nlm.nih.gov/pubmed/21877753
http://dx.doi.org/10.1021/ci2001428

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