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Scaffold Diversity of Exemplified Medicinal Chemistry Space
[Image: see text] The scaffold diversity of 7 representative commercial and proprietary compound libraries is explored for the first time using both Murcko frameworks and Scaffold Trees. We show that Level 1 of the Scaffold Tree is useful for the characterization of scaffold diversity in compound li...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180201/ https://www.ncbi.nlm.nih.gov/pubmed/21877753 http://dx.doi.org/10.1021/ci2001428 |