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A translational continuum of model systems for evaluating treatment strategies in Alzheimer’s disease: isradipine as a candidate drug

A growing body of evidence supports the ‘calcium hypothesis’ of Alzheimer’s disease (AD), which postulates that a variety of insults might disrupt the homeostatic regulation of neuronal calcium (Ca(2+)) in the brain, resulting in the progressive symptoms that typify the disease. However, despite ong...

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Detalles Bibliográficos
Autores principales: Copenhaver, Philip F., Anekonda, Thimmappa S., Musashe, Derek, Robinson, Kristine M., Ramaker, Jenna M., Swanson, Tracy L., Wadsworth, Teri L., Kretzschmar, Doris, Woltjer, Randall L., Quinn, Joseph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180227/
https://www.ncbi.nlm.nih.gov/pubmed/21596710
http://dx.doi.org/10.1242/dmm.006841