Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson’s disease

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder. Oxidative stress has been associated with the etiology of both sporadic and monogenic forms of PD. The transcription factor Nrf2, a conserved global regulator of cellular antioxidant responses, has been implicated in ne...

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Detalles Bibliográficos
Autores principales: Barone, Maria Cecilia, Sykiotis, Gerasimos P., Bohmann, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2011
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180234/
https://www.ncbi.nlm.nih.gov/pubmed/21719443
http://dx.doi.org/10.1242/dmm.007575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180234/
https://www.ncbi.nlm.nih.gov/pubmed/21719443
http://dx.doi.org/10.1242/dmm.007575

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