Identifying Compound-Target Associations by Combining Bioactivity Profile Similarity Search and Public Databases Mining

[Image: see text] Molecular target identification is of central importance to drug discovery. Here, we developed a computational approach, named bioactivity profile similarity search (BASS), for associating targets to small molecules by using the known target annotations of related compounds from pu...

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Detalles Bibliográficos
Autores principales: Cheng, Tiejun, Li, Qingliang, Wang, Yanli, Bryant, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180241/
https://www.ncbi.nlm.nih.gov/pubmed/21834535
http://dx.doi.org/10.1021/ci200192v

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180241/
https://www.ncbi.nlm.nih.gov/pubmed/21834535
http://dx.doi.org/10.1021/ci200192v

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