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Methyl-binding domain protein-based DNA isolation from human blood serum combines DNA analyses and serum-autoantibody testing

BACKGROUND: Circulating cell free DNA in serum as well as serum-autoantibodies and the serum proteome have great potential to contribute to early cancer diagnostics via non invasive blood tests. However, most DNA preparation protocols destroy the protein fraction and therefore do not allow subsequen...

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Detalles Bibliográficos
Autores principales: Wielscher, Matthias, Pulverer, Walter, Peham, Johannes, Hofner, Manuela, Rappaport, Christine F, Singer, Christian, Jungbauer, Christof, Nöhammer, Christa, Weinhäusel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180258/
https://www.ncbi.nlm.nih.gov/pubmed/21896199
http://dx.doi.org/10.1186/1472-6890-11-11