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Gα(i2)- and Gα(i3)-Specific Regulation of Voltage-Dependent L-Type Calcium Channels in Cardiomyocytes

BACKGROUND: Two pertussis toxin sensitive G(i) proteins, G(i2) and G(i3), are expressed in cardiomyocytes and upregulated in heart failure. It has been proposed that the highly homologous G(i) isoforms are functionally distinct. To test for isoform-specific functions of G(i) proteins, we examined th...

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Detalles Bibliográficos
Autores principales: Dizayee, Sara, Kaestner, Sonja, Kuck, Fabian, Hein, Peter, Klein, Christoph, Piekorz, Roland P., Meszaros, Janos, Matthes, Jan, Nürnberg, Bernd, Herzig, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180279/
https://www.ncbi.nlm.nih.gov/pubmed/21966394
http://dx.doi.org/10.1371/journal.pone.0024979