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IL-4 Amplifies the Pro-Inflammatory Effect of Adenosine in Human Mast Cells by Changing Expression Levels of Adenosine Receptors

Adenosine inhalation produces immediate bronchoconstriction in asthmatics but not in normal subjects. The bronchospastic effect of adenosine is largely mediated through adenosine-induced mast cell activation, the mechanism of which is poorly understood due to limitations in culturing human primary m...

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Detalles Bibliográficos
Autores principales: Hua, Xiaoyang, Chason, Kelly D., Patel, Janki Y., Naselsky, Warren C., Tilley, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180290/
https://www.ncbi.nlm.nih.gov/pubmed/21966389
http://dx.doi.org/10.1371/journal.pone.0024947