Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model

Rett syndrome (RTT) is an autism spectrum developmental disorder caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Excellent RTT mouse models have been created to study the disease mechanisms, leading to many important findings with potential therapeutic implications. Th...

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Detalles Bibliográficos
Autores principales: Ananiev, Gene, Williams, Emily Cunningham, Li, Hongda, Chang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180386/
https://www.ncbi.nlm.nih.gov/pubmed/21966470
http://dx.doi.org/10.1371/journal.pone.0025255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180386/
https://www.ncbi.nlm.nih.gov/pubmed/21966470
http://dx.doi.org/10.1371/journal.pone.0025255

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