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Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

Artesunate (AS) is a clinically versatile artemisinin derivative utilized for the treatment of mild to severe malaria infection. Given the therapeutic significance of AS and the necessity of appropriate AS dosing, substantial research has been performed investigating the pharmacokinetics of AS and i...

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Detalles Bibliográficos
Autores principales: Morris, Carrie A, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Jung, Donald, Shin, Chang-Sik, Fleckenstein, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180444/
https://www.ncbi.nlm.nih.gov/pubmed/21914160
http://dx.doi.org/10.1186/1475-2875-10-263